J. Ansel, H. Bottin, C. Rodriguez-beltran, C. Damon, M. Nagarajan et al., Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait, PLoS Genetics, vol.35, issue.2, 2008.
DOI : 10.1371/journal.pgen.1000049.s006

URL : https://hal.archives-ouvertes.fr/ensl-00272739

Y. E. Antebi, S. Reich-zeliger, Y. Hart, A. Mayo, I. Eizenberg et al., Mapping Differentiation under Mixed Culture Conditions Reveals a Tunable Continuum of T Cell Fates, PLoS Biology, vol.11, issue.8, 2013.
DOI : 10.1371/journal.pbio.1001616.s020

R. Bahar, C. H. Hartmann, K. A. Rodriguez, A. D. Denny, R. A. Busuttil et al., Increased cell-to-cell variation in gene expression in ageing mouse heart, Nature, vol.11, issue.7096, pp.1011-1014, 1038.
DOI : 10.1038/nature04844

L. Bai, G. Charvin, E. D. Siggia, and F. R. Cross, Nucleosome-Depleted Regions in Cell-Cycle-Regulated Promoters Ensure Reliable Gene Expression in Every Cell Cycle, Developmental Cell, vol.18, issue.4, pp.544-555, 2010.
DOI : 10.1016/j.devcel.2010.02.007

N. Q. Balaban, J. Merrin, R. Chait, L. Kowalik, and S. Leibler, Bacterial Persistence as a Phenotypic Switch, Science, vol.305, issue.5690, pp.1622-1625, 2004.
DOI : 10.1126/science.1099390

A. Bar-even, J. Paulsson, N. Maheshri, M. Carmi, E. O-'shea et al., Noise in protein expression scales with natural protein abundance, Nature Genetics, vol.15, issue.6, pp.636-643, 1038.
DOI : 10.1073/pnas.092538799

N. Barkai and S. Leibler, Circadian clocks limited by noise, Nature, vol.403, pp.267-268, 2000.

N. N. Batada, L. D. Hurst, H. J. Beaumont, J. Gallie, C. Kost et al., Evolution of chromosome organization driven by selection for reduced gene expression noise, Nature Genetics, vol.418, issue.8, pp.945-949, 1038.
DOI : 10.1038/ng2071

A. Becskei, B. B. Kaufmann, and A. Van-oudenaarden, Contributions of low molecule number and chromosomal positioning to stochastic gene expression, Nature Genetics, vol.3, issue.9, pp.937-944, 2005.
DOI : 10.1002/bies.950171112

A. Becskei and L. Serrano, Engineering stability in gene networks by autoregulation, Nature, vol.405, issue.6786, pp.590-593, 2000.
DOI : 10.1038/35014651

W. J. Blake, G. Balázsi, M. A. Kohanski, F. J. Isaacs, K. F. Murphy et al., Phenotypic Consequences of Promoter-Mediated Transcriptional Noise, Molecular Cell, vol.24, issue.6, pp.853-865, 2006.
DOI : 10.1016/j.molcel.2006.11.003

C. Bönisch and S. B. Hake, Histone H2A variants in nucleosomes and chromatin: more or less stable? Nucleic Acids Res, pp.10719-10741, 2012.

C. Braendle and M. A. Félix, Plasticity and Errors of a Robust Developmental System in Different Environments, Developmental Cell, vol.15, issue.5, 2008.
DOI : 10.1016/j.devcel.2008.09.011

URL : https://hal.archives-ouvertes.fr/hal-00339142

Y. Buganim, D. A. Faddah, A. W. Cheng, E. Itskovich, S. Markoulaki et al., Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase, Cell, vol.150, issue.6, pp.1209-1222, 2012.
DOI : 10.1016/j.cell.2012.08.023

L. Cai, C. K. Dalal, and M. B. Elowitz, Frequency-modulated nuclear localization bursts coordinate gene regulation, Nature, vol.131, issue.7212, pp.485-490, 2008.
DOI : 10.1038/nature07292

L. B. Carey, D. Van-dijk, P. M. Sloot, J. A. Kaandorp, and E. Segal, Promoter Sequence Determines the Relationship between Expression Level and Noise, PLoS Biology, vol.19, issue.4, 2013.
DOI : 10.1371/journal.pbio.1001528.s013

A. J. Carter and D. Houle, ARTIFICIAL SELECTION REVEALS HERITABLE VARIATION FOR DEVELOPMENTAL INSTABILITY, Evolution, vol.265, issue.12, pp.3558-3564, 2011.
DOI : 10.1111/j.1558-5646.2011.01393.x

M. Venable and D. , Transcriptome-wide noise controls lineage choice in mammalian progenitor cells doi: 10 Seed germination in desert annuals: an empirical test of adaptive bet hedging, Nature Am. Nat, vol.453, issue.155, pp.544-547, 1038.

D. Coleman-derr and D. Zilberman, Deposition of Histone Variant H2A.Z within Gene Bodies Regulates Responsive Genes, PLoS Genetics, vol.8, issue.10, 2012.
DOI : 10.1371/journal.pgen.1002988.s028

R. D. Dar, N. N. Hosmane, M. R. Arkin, R. F. Siliciano, and L. S. Weinberger, Screening for noise in gene expression identifies drug synergies, Science, vol.344, issue.6190, pp.1392-1396, 2014.
DOI : 10.1126/science.1250220

E. Dessaud, V. Ribes, N. Balaskas, L. L. Yang, A. Pierani et al., Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog, PLoS Biology, vol.65, issue.6, 2010.
DOI : 10.1371/journal.pbio.1000382.s005

D. M. Eisenmann, Wnt signaling, The C. elegans Research Community, 2005.
DOI : 10.1895/wormbook.1.7.1

A. Eldar, V. K. Chary, P. Xenopoulos, M. E. Fontes, O. C. Loson et al., Partial penetrance facilitates developmental evolution in bacteria, Nature, vol.190, pp.510-514, 1038.
DOI : 10.1038/nature08150

M. B. Elowitz, A. J. Levine, E. D. Siggia, and P. S. Swain, Stochastic Gene Expression in a Single Cell, Science, vol.297, issue.5584, pp.1183-1186, 2002.
DOI : 10.1126/science.1070919

S. Fehrmann, H. Bottin-duplus, A. Leonidou, E. Mollereau, A. Barthelaix et al., Natural sequence variants of yeast environmental sensors confer cell-to-cell expression variability, Molecular Systems Biology, vol.61, issue.1, 2013.
DOI : 10.1038/msb.2009.58

URL : https://hal.archives-ouvertes.fr/ensl-00872339

M. A. Félix, Cryptic Quantitative Evolution of the Vulva Intercellular Signaling Network in Caenorhabditis, Current Biology, vol.17, issue.2, 2007.
DOI : 10.1016/j.cub.2006.12.024

M. A. Félix and A. Wagner, Robustness and evolution: concepts, insights and challenges from a developmental model system, Heredity, vol.154, issue.2, 2008.
DOI : 10.1126/science.7652556

A. Fernández, M. Lynch, M. Francesconi, and B. Lehner, Non-adaptive origins of interactome complexity, Nature, vol.10, issue.7352, pp.502-505, 1038.
DOI : 10.1038/nature09992

H. B. Fraser, A. E. Hirsh, G. Giaever, J. Kumm, and M. B. Eisen, Noise Minimization in Eukaryotic Gene Expression, PLoS Biology, vol.99, issue.6, 2004.
DOI : 10.1371/journal.pbio.0020137.st001

M. W. Gray, J. Luke?, J. M. Archibald, P. J. Keeling, and W. F. Doolittle, Irremediable Complexity?, Science, vol.330, issue.6006, pp.920-921, 2010.
DOI : 10.1126/science.1198594

S. Hardy, P. É. Jacques, N. Gévry, A. Forest, M. È. Fortin et al., The Euchromatic and Heterochromatic Landscapes Are Shaped by Antagonizing Effects of Transcription on H2A.Z Deposition, PLoS Genetics, vol.12, issue.10, 2009.
DOI : 10.1371/journal.pgen.1000687.s020

G. Hornung, R. Bar-ziv, D. Rosin, N. Tokuriki, D. S. Tawfik et al., Noise-mean relationship in mutated promoters, Genome Research, vol.22, issue.12, pp.2409-2417, 2012.
DOI : 10.1101/gr.139378.112

A. M. Hulse and J. J. Cai, Genetic Variants Contribute to Gene Expression Variability in Humans, Genetics, vol.193, issue.1, 2013.
DOI : 10.1534/genetics.112.146779

J. D. Jackson and M. A. Gorovsky, Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants, Nucleic Acids Research, vol.28, issue.19, pp.3811-3816, 2000.
DOI : 10.1093/nar/28.19.3811

J. M. Jimenez-gomez, J. A. Corwin, B. Joseph, J. N. Maloof, and D. J. Kliebenstein, Genomic Analysis of QTLs and Genes Altering Natural Variation in Stochastic Noise, PLoS Genetics, vol.19, issue.9, 2011.
DOI : 10.1371/journal.pgen.1002295.s005

J. Jo, H. Kang, M. Y. Choi, and D. S. Koh, How Noise and Coupling Induce Bursting Action Potentials in Pancreatic ??-Cells, Biophysical Journal, vol.89, issue.3, pp.1534-1542, 2005.
DOI : 10.1529/biophysj.104.053181

V. Katju and U. Bergthorsson, Copy-number changes in evolution: rates, fitness effects and adaptive significance, Frontiers in Genetics, vol.4, 2013.
DOI : 10.3389/fgene.2013.00273

P. M. Kim, A. Sboner, Y. Xia, and M. Gerstein, The role of disorder in interaction networks: a structural analysis, Molecular Systems Biology, vol.4, p.16, 2008.
DOI : 10.1021/pr060392u

E. T. Kipreos, C. elegans cell cycles: invariance and stem cell divisions, Nature Reviews Molecular Cell Biology, vol.126, issue.10, pp.766-776, 1038.
DOI : 10.1016/j.ydbio.2003.12.023

J. J. Kupiec, A chance-selection model for cell differentiation, Cell Death Differ, vol.3, pp.385-390, 1996.

E. Kussell and S. Leibler, Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments, Science, vol.309, issue.5743, pp.2075-2078, 2005.
DOI : 10.1126/science.1114383

B. Lehner, Selection to minimise noise in living systems and its implications for the evolution of gene expression, Molecular Systems Biology, vol.154, p.11, 2008.
DOI : 10.1038/ng1819

B. Lehner, Conflict between Noise and Plasticity in Yeast, PLoS Genetics, vol.6, issue.11, 2010.
DOI : 10.1371/journal.pgen.1001185.s012

S. F. Levy and M. L. Siegal, Network Hubs Buffer Environmental Variation in Saccharomyces cerevisiae, PLoS Biology, vol.17, issue.11, 2008.
DOI : 10.1371/journal.pbio.0060264.st003

S. F. Levy, N. Ziv, and M. L. Siegal, Bet Hedging in Yeast by Heterogeneous, Age-Correlated Expression of a Stress Protectant, PLoS Biology, vol.10, issue.5, 2012.
DOI : 10.1371/journal.pbio.1001325.s018

J. Luke?, J. M. Archibald, P. J. Keeling, W. F. Doolittle, and M. W. Gray, How a neutral evolutionary ratchet can build cellular complexity, IUBMB Life, vol.461, issue.7, pp.528-537, 2011.
DOI : 10.1002/iub.489

M. Lynch, Evolutionary diversification of the multimeric states of proteins, Proceedings of the National Academy of Sciences, vol.110, issue.30, pp.2821-2828, 2013.
DOI : 10.1073/pnas.1310980110

K. F. Murphy, G. Balázsi, C. , and J. J. , Combinatorial promoter design for engineering noisy gene expression, Proceedings of the National Academy of Sciences, vol.104, issue.31, pp.12726-12731, 2007.
DOI : 10.1073/pnas.0608451104

J. R. Newman, S. Ghaemmaghami, J. Ihmels, D. K. Breslow, M. Noble et al., Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise Epigenetic and conventional regulation is distributed among activators of FLO11 allowing tuning of population-level heterogeneity in its expression, Nature PLoS Genet, vol.441, pp.840-846, 2006.

Y. Okabe-oho, H. Murakami, S. Oho, and M. Sasai, Stable, Precise, and Reproducible Patterning of Bicoid and Hunchback Molecules in the Early Drosophila Embryo, PLoS Computational Biology, vol.440, issue.8, 2009.
DOI : 10.1371/journal.pcbi.1000486.s008

B. Ordas, R. Malvar, and W. G. Hill, Genetic variation and quantitative trait loci associated with developmental stability and the environmental correlation between traits in maize, Genetics Research, vol.118, issue.05, pp.385-395, 2008.
DOI : 10.1534/genetics.104.032375

L. Pillus and J. And-rine, Epigenetic inheritance of transcriptional states in S. cerevisiae, Cell, vol.59, issue.4, pp.637-647, 1989.
DOI : 10.1016/0092-8674(89)90009-3

J. M. Raser, O. Shea, and E. K. , Control of Stochasticity in Eukaryotic Gene Expression, Science, vol.304, issue.5678, pp.1811-1814, 2004.
DOI : 10.1126/science.1098641

J. B. Richardson, L. D. Uppendahl, M. K. Traficante, S. F. Levy, and M. L. Siegal, Histone Variant HTZ1 Shows Extensive Epistasis with, but Does Not Increase Robustness to, New Mutations, PLoS Genetics, vol.317, issue.8, 2013.
DOI : 10.1371/journal.pgen.1003733.s014

M. Ros, D. Sorensen, R. Waagepetersen, M. Dupont-nivet, M. Sancristobal et al., Evidence for Genetic Control of Adult Weight Plasticity in the Snail Helix aspersa, Genetics, vol.168, issue.4, pp.2089-2097, 2004.
DOI : 10.1534/genetics.104.032672

M. S. Santisteban, M. Hang, and M. M. Smith, Histone Variant H2A.Z and RNA Polymerase II Transcription Elongation, Molecular and Cellular Biology, vol.31, issue.9, pp.1848-1860, 2011.
DOI : 10.1128/MCB.01346-10

A. M. Simons, Fluctuating natural selection accounts for the evolution of diversification bet hedging, Proceedings of the Royal Society B: Biological Sciences, vol.88, issue.5, pp.1006-1495, 1890.
DOI : 10.1890/06-1495

A. M. Simons, Modes of response to environmental change and the elusive empirical evidence for bet hedging, Proceedings of the Royal Society B: Biological Sciences, vol.32, issue.6644, pp.1601-1609, 2011.
DOI : 10.1038/41996

J. Stewart-ornstein, J. S. Weissman, and H. Samad, Cellular Noise Regulons Underlie Fluctuations in Saccharomyces cerevisiae, Molecular Cell, vol.45, issue.4, 2012.
DOI : 10.1016/j.molcel.2011.11.035

D. M. Suter, N. Molina, D. Gatfield, K. Schneider, U. Schibler et al., Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics, Science, vol.332, issue.6028, pp.472-474, 2011.
DOI : 10.1126/science.1198817

M. Thattai and A. Van-oudenaarden, Stochastic Gene Expression in Fluctuating Environments, Genetics, vol.167, issue.1, pp.523-530, 2004.
DOI : 10.1534/genetics.167.1.523

T. L. To and N. Maheshri, Noise Can Induce Bimodality in Positive Transcriptional Feedback Loops Without Bistability, Science, vol.327, issue.5969, pp.1142-1145, 2010.
DOI : 10.1126/science.1178962

V. N. Uversky and A. K. Dunker, Understanding protein non-folding, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1804, issue.6, 2010.
DOI : 10.1016/j.bbapap.2010.01.017

J. Viñuelas, G. Kaneko, A. Coulon, E. Vallin, V. Morin et al., Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts, BMC Biology, vol.11, issue.1, pp.15-25, 2013.
DOI : 10.1038/nprot.2009.64

D. Volfson, J. Marciniak, W. J. Blake, N. Ostroff, L. S. Tsimring et al., Origins of extrinsic variability in eukaryotic gene expression, Nature, vol.175, issue.7078, pp.861-864, 1038.
DOI : 10.1021/j100540a008

Z. Wang and J. Zhang, Impact of gene expression noise on organismal fitness and the efficacy of natural selection, Proceedings of the National Academy of Sciences, vol.108, issue.16, pp.67-76, 2011.
DOI : 10.1073/pnas.1100059108

J. J. Ward, J. S. Sodhi, L. J. Mcguffin, B. F. Buxton, and D. T. Jones, Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life, Journal of Molecular Biology, vol.337, issue.3, pp.635-645, 2004.
DOI : 10.1016/j.jmb.2004.02.002

C. M. Weber, S. Ramachandran, and S. Henikoff, Nucleosomes are contextspecific , H2A.Z-modulated barriers to RNA polymerase, Mol. Cell, vol.53, 2014.

L. Weinberger, Y. Voichek, I. Tirosh, G. Hornung, I. Amit et al., Expression Noise and Acetylation Profiles Distinguish HDAC Functions, Molecular Cell, vol.47, issue.2, 2012.
DOI : 10.1016/j.molcel.2012.05.008

M. F. Wernet, E. O. Mazzoni, A. Çelik, D. M. Duncan, I. Duncan et al., Stochastic spineless expression creates the retinal mosaic for colour vision, Nature, vol.27, issue.7081, pp.174-180, 1038.
DOI : 10.1038/nature04615

E. Y. Xu, K. A. Zawadzki, and J. R. Broach, Single-Cell Observations Reveal Intermediate Transcriptional Silencing States, Molecular Cell, vol.23, issue.2, 2006.
DOI : 10.1016/j.molcel.2006.05.035

G. Yvert, ???Particle genetics???: treating every cell as unique, Trends in Genetics, vol.30, issue.2, pp.49-56, 2014.
DOI : 10.1016/j.tig.2013.11.002

G. Yvert, S. Ohnuki, S. Nogami, Y. Imanaga, S. Fehrmann et al., Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast, BMC Systems Biology, vol.7, issue.1, pp.54-64, 2013.
DOI : 10.1128/EC.00012-07

URL : https://hal.archives-ouvertes.fr/ensl-00962348

Z. Zhang, W. Qian, and J. Zhang, Positive selection for elevated gene expression noise in yeast, Molecular Systems Biology, vol.97, p.58, 2009.
DOI : 10.1186/gb-2003-4-4-r28

N. Ziv, M. L. Siegal, and D. Gresham, Genetic and Nongenetic Determinants of Cell Growth Variation Assessed by High-Throughput Microscopy, Molecular Biology and Evolution, vol.30, issue.12, pp.2568-2578, 2013.
DOI : 10.1093/molbev/mst138