HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

CST Meets Shelterin to Keep Telomeres in Check

Abstract : Telomere protection in budding yeast requires the heterotrimer named CST (for Cdc13-Stn1-Ten1). Recent data show that CST components are conserved and required for telomere stability in a wide range of eukaryotes, even those utilizing the shelterin complex to protect their telomeres. A common function of these proteins might be to stimulate priming at the C-strand gap that remains after telomerase elongation, replication termination, and terminal processing. In light of the budding yeast situation, another conserved function of CST might well be the regulation of telomerase. The cohabitation at telomeres of CST and shelterin components highlights the complexity of telomere biology.
Document type :
Journal articles
Complete list of metadata

https://hal-ens-lyon.archives-ouvertes.fr/ensl-00815741
Contributor : Agnès Ganivet Connect in order to contact the contributor
Submitted on : Friday, April 19, 2013 - 12:11:36 PM
Last modification on : Sunday, May 1, 2022 - 3:14:31 AM

Identifiers

  • HAL Id : ensl-00815741, version 1

Collections

Citation

Marie-Josèphe Giraud-Panis, M. Teresa Teixeira, Vincent Géli, Eric Gilson. CST Meets Shelterin to Keep Telomeres in Check. Molecular Cell, Cell Press, 2010, 39 (5), pp.665-676. ⟨ensl-00815741⟩

Share

Metrics

Record views

35