Relevance of a scoring system including CD11c expression in the identification of splenic diffuse red pulp small B-cell lymphoma (SRPL)

Abstract : 'Splenic red pulp lymphoma with numerous basophilic villous lymphocytes' (SRPL), recently described, is characterized by clinical, morphologic, immunologic, cytogenetic and molecular features distinct from SMZL/SLVL and HCL. In particular, the intensity of CD11c staining (expressed as fluorescence intensity -RFI-) in SRPL is significantly different from the RFI in SMZL/SLVL and HCL. Moreover the use of a scoring system based on the expression of CD11c, CD22, CD76, CD38 and CD27 appears to improve the differential diagnosis between SRPL and SMZL/SLVL and emphasizes that SRPL is an entity closed to but distinct from SMZL/SLVL. Copyright © 2010 John Wiley & Sons, Ltd.
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Article dans une revue
Hematological Oncology, Wiley, 2011, 29 (1), pp.47-51. 〈10.1002〉
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https://hal-ens-lyon.archives-ouvertes.fr/ensl-00808949
Contributeur : Agnès Ganivet <>
Soumis le : lundi 8 avril 2013 - 11:37:02
Dernière modification le : jeudi 8 février 2018 - 11:09:30

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  • HAL Id : ensl-00808949, version 1
  • DOI : 10.1002

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Lucile Baseggio, Alexandra Traverse-Glehen, Evelyne Callet-Bauchu, Dominique Morel, Jean-Pierre Magaud, et al.. Relevance of a scoring system including CD11c expression in the identification of splenic diffuse red pulp small B-cell lymphoma (SRPL). Hematological Oncology, Wiley, 2011, 29 (1), pp.47-51. 〈10.1002〉. 〈ensl-00808949〉

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